Science Literature
Post details: Revealing the mystery of the bacterial flagellum
11/03/05
Revealing the mystery of the bacterial flagellum
Revealing the mystery of the bacterial flagellum:
A self-assembling nanomachine with fine switching capability
JAPAN NANONET BULLETIN - 11th Issue - February 5, 2004
Keiichi NAMBA
Professor, Graduate School of Frontier Biosciences, Osaka University
(Issued in Japanese: March 25, 2003)
(the online article contains links to many fasinating animations of the bacterial flagellum)
Nature created a rotary motor with a diameter of 30 nm. Motility of bacteria, such as Salmonella and E. coli with a body size of 1 to 2 micron, is driven by rapid rotation of a helical propeller by such a tiny little motor at its base. This organelle is called the flagellum, made of a rotary motor and a thin helical filament that grows up to about 15 micron. It rotates at around 20,000 rpm, at energy consumption of only around 10 to 16 W and with energy conversion efficiency close to 100 percent. Prof. Nambas research group is going to reveal the mechanism of this highly efficient flagellar motor that is far beyond the capabilities of artificial motors.
The flagellum is made by self-assembly of about 25 different proteins. The rotor ring made of protein FliF is the first to assemble in the cytoplasmic membrane. Then, other protein molecules attach to the ring one after another from the base to the tip to construct the motor structure. After the motor has been formed, the flagellar filament, which functions as a helical propeller, is assembled. Precise recognition of the template structure by component proteins allows this highly ordered self-assembly process to proceed without error. The flagellar filament is made of 20,000 to 30,000 copies of flagellin polymerized into a helical tube structure. Flagellin molecules are transported through a long narrow central channel of the flagellum from the cell interior to the distal end of the flagellum, where they self-assemble in a helical manner by the help of a cap complex. The cap is pentameric complex made of HAP2 and has a pentagonal plate and five leg domains, whose flexible stepping movements accompanied by rotation of the whole cap is the key mechanism to promote the efficient self-assembly of flagellin molecules by preparing just one binding site of flagellin at a time and guiding the binding.
Science Literature
| Mon | Tue | Wed | Thu | Fri | Sat | Sun |
|---|---|---|---|---|---|---|
| << < | > >> | |||||
| 1 | 2 | 3 | 4 | 5 | ||
| 6 | 7 | 8 | 9 | 10 | 11 | 12 |
| 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| 20 | 21 | 22 | 23 | 24 | 25 | 26 |
| 27 | 28 | 29 | 30 | 31 | ||
Search
Categories
Archives
- May 2013 (2)
- April 2013 (1)
- March 2013 (2)
- February 2013 (3)
- January 2013 (2)
- December 2012 (2)
- November 2012 (4)
- October 2012 (4)
- September 2012 (1)
- August 2012 (1)
- July 2012 (2)
- June 2012 (4)
- more...
Linkblog
Links - Groups and Organizations
- Access Research Network
- Discovery Institute
- Evolution News Blog
Evolution has become a favorite topic of the news media recently, but for some reason, they never seem to get the story straight. The staff at Discovery Institute's Center for Science and Culture started this Blog to set the record straight and make sure you knew "the rest of the story".
- Intelligent Design Network (IDNet)
- Intelligent Design Undergraduate Research Center
- Intelligent Reasoning
A blogger from New England offers his intelligent reasoning.
- International Society for Complexity, Information, and Design (ISCID)
- Telic Thoughts
We are a group of individuals, coming from diverse backgrounds and not speaking for any organization, who have found common ground around teleological concepts, including intelligent design. We think these concepts have real potential to generate insights about our reality that are being drowned out by political advocacy from both sides. We hope this blog will provide a small voice that helps rectify this situation.
- The Design Inference - The Writings of William A. Dembski
- The Intelligent Design and Evolution Awareness Center (IDEA)
- www.themonkeytrial.com
Website dedicated to comparing scenes from the "Inherit the Wind" movie with factual information from actual Scopes Trial. View 37 clips from the movie and decide for yourself if this movie is more fact or fiction.
Links - Of General Interest
- A Brief View of Time and Those That Live There
Don Cicchetti blogs on: Culture, Music, Faith, Intelligent Design, Guitar, Audio
- A Quick Guide to Sequenced Genomes
- ARN Related Web Links
- Creation/Evolution Quotes
Australian biologist Stephen E. Jones maintains one of the best origins "quote" databases around. He is meticulous about accuracy and working from original sources.
- CreationEvolutionDesign
Most guys going through midlife crisis buy a convertible. Austrialian Stephen E. Jones went back to college to get a biology degree and is now a proponent of ID and common ancestry.
- Darwinian Fairytales by David Stove
Complete zipped downloadable pdf copy of David Stove's devastating, and yet hard-to-find, critique of neo-Darwinism entitled "Darwinian Fairytales"
- ID The Future
Intelligent Design The Future is a multiple contributor weblog whose participants include the nation's leading design scientists and theorists: biochemist Michael Behe, mathematician William Dembski, astronomer Guillermo Gonzalez, philosophers of science Stephen Meyer, and Jay Richards, philosopher of biology Paul Nelson, molecular biologist Jonathan Wells, and science writer Jonathan Witt. Posts will focus primarily on the intellectual issues at stake in the debate over intelligent design, rather than its implications for education or public policy.
- John Mark Reynolds Blog
A Philosopher's Journey: Political and cultural reflections of John Mark N. Reynolds. Dr. Reynolds is Director of the Torrey Honors Institute at
Biola University.
- NASA Astronomy Picture of the Day
Misc
Syndicate this blog 
What is RSS?
powered by
Original template design by François PLANQUE.
